Beeinflussung von sekretorischen IgA-Defiziten bei Sportstudierenden durch Nahrungsergänzungsmittel

Author(s): Rosler, P., Lachtermann, E., Jung, K.

Abstract: The secretory immunoglobulin A (sIgA) is regarded as an essential component of the endogenous immune defense in the intestine. The mineral substances magnesium and zinc are said to influence the immune system as well. Due to excessive sports activities, stress in connection with studies and a malnutrition, many sport students showed an insufficient endogenous immune defense in the intestine.The present study with 118 sport students revealed a deficiency of sIgA in the stool specimen of 53 test subjects (44.9 %). Of these tests subjects, 52 participated in the study. The aim of the study was to find out, whether an intake of selected food supplements during a period of four weeks could influence the deficit of sIgA, which was present in these test subjects.The participants with a deficiency of sIgA were divided into three groups. 20 test subjects of the first group took the probiotic substance Lactobact, 16 test subjects took magnesium and zinc, and the remaining 16 test subjects took all three preparations, Lactobact plus magnesium and zinc.In all three groups there was an increase in the content of sIgA in the stool specimen, which was statistically noticeable in the Lactobact group (43 % of the people participating in the test) and Lactobact/magnesium/zinc group (46 % of the people participating in the test). In the magnesium/zinc group a statistically insignificant increase in sIgA for 25 % was discovered. So, the result after a four week intake of Lactobact was a significant increase in the sIgA values and therefore a clear strengthening of the endogenous defense at the intestinal mucosa, while the only substitution with magnesium and zinc was not enough to normalize the sIgA values.

Keyword(s): Darmflora

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