What are the functional deficits produced by hippocampal and perirhinal cortex lesions?

Author(s): vanEijk, R., Gooding, P. A., Isaac, C. L., Holdstock, J. S.

Journal/Book: Behav Brain Sci. 1999; 22: 40 West 20Th Street, New York, NY 10011-4211, USA. Cambridge Univ Press. 460+.

Abstract: A hippocampal patient is described who shows preserved item recognition and simple recognition-based recollection but impaired recall and associative recognition. These data and other evidence suggest that contrary to Aggleton & Brown's target article, Papez circuit damage impairs only complex item-item-context recollection. A patient with perirhinal cortex damage and a delayed global memory deficit, apparently inconsistent with A&B's framework, is also described.

Note: Editorial Mayes AR, Univ Sheffield, Royal Hallamshire Hosp, Dept Clin Neurol, Sheffield S10 2JF, S Yorkshire, ENGLAND

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