Brain functions and psychiatric disorders

Author(s): Othmer, P., Othmer, S. C.

Journal/Book: Psychiat Clin N Amer. 1998; 21: Independence Square West, Curtis Center, Ste 300, Philadelphia, PA 19106-3399. W B Saunders Co. 517.

Abstract: Psychiatric disorders are viewed as brain disorders affecting five circuits of the brain: the brainstem, the hypothalamus, the motor striatum, the limbic system (ventral striatum), and the neocortex. This five-circuit model combines neuroscientific, psychopharmacologic, evolutionary, introspective, and behavioral data. The article presents a broad speculative overview of some brain functions and dysfunctions relevant for clinicians.

Note: Review Othmer E, Picture Hills Psychiat Ctr, 5709 NW 64TH Terrace, Kansas City,MO 64151 USA

Keyword(s): OBSESSIVE-COMPULSIVE DISORDER; POSITRON EMISSION TOMOGRAPHY; CEREBRAL BLOOD-FLOW; POSTTRAUMATIC-STRESS-DISORDER; GRAY-MATTER VOLUME; ADRENERGIC-RECEPTOR BINDING; SECTION ELECTRON-MICROSCOPY; GLUCOSE METABOLIC RATES; COMPUTED-TOMOGRAPHY; PREFRONTAL CORTEX

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Brain functions and psychiatric disorders - A clinical view