Klinische Effekte der externen Therapie mit Roßkastaniensamenextrakt bei Patienten mit chronisch-venöser Insuffizienz

Author(s): C. , L., J. , E. , Metzner, C. -J. , R.

Journal/Book: Ärztezeitschrift für Naturheilverfahren. 1995; 36/8: 566-576.

Abstract: Tolerance and efficacy of three finished drug forms containig horse chestnut seed extract in patients with first and second degree chronic venous insufficiency was tested in a total of 45 patients in a comparison with the reference preparation heparin 120000 and placebo preparations. The parameters investigated included tolerance on the basis of epicutaneous testing, evaluation of local tolerance by medical investigator and patient and of therapeutic efficacy on the basis of circumference of lower, middle and upper thigh, data from light reflection rheography, venous filling time (to), degree of cutaneous reflection (delta R) and clinical findings. With regard to tolerance, it was seen that the three test preparations, the reference preparation and the placebo preparations can be classified as non-dermatotoxic for acute applications. The test preparations tolerated well to very well. With the three topical preparations containing horse chestnut extract, a tendency to improvement of prior findings was determined along with improvement of sujective patient condition.

Keyword(s): chronisch-venöse Insuffizienz, Roßkastaniensamenextrakt-Therapie, Heparintherapie, Licht-Reflexions-Rheographie

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