Artischockenblätterextrakt - Lipidsenkung auf pflanzlicher Basis

Author(s): M. , S.

Journal/Book: Ärztezeitschrift für Naturheilverfahren. 1995; 36/5: 378-389.

Abstract: In recent pharmacological and clinical studies as well as in numerous medical case reports and historical reviews, the efficacy of extreacts of artichoke leaves (Cynara scolymus L.) was documented. Up to now, choleretic, lipid lowering and hepatoprotective effects were shown, as well as distinct effects against dyspeptic disorders. The antidyspeptic effects mainly are attributed to an increase in choleresis, as was demonstrated in clinical double blind studies. In addition, the total extract from artichoke leaves, with the leading substance cynarine (1,5-dicalleoylquinic acid), is a phytotherapeutic drug without side effects, which can be used for the long-term treatment of disturbances of lipid metabolsim. The efficacy could be shown in in vitro experiments as well as in clinical studies and experiments on animals. Actual results indicate an inhibition of plaque-forming oxidated low density lipoprotein (LDL), and therefore relevant atherosclerosis preventing effects, which would present a clinically significant extention of the to date knowing therapeutic spectrum of artichoke leaves extract. In single cases already existing atherosclerotic depositions showed tendencies to involute.

Keyword(s): Artischockenblätter, Cynara scolymus L., Lipidsenkung, Atheroskleroseprävention, Cholerese, Dyspepsie, hepatoprotektive Wirkung

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