Ginkgo biloba. Wirksamkeit eines Spezialextraktes bei Patienten mit zerebraler Insuffizienz

Journal/Book: Münchener Medizinische Wochenschrift. 1991; 133: 190-194.

Abstract: Judgement of Well-being and Psychometric Tests in Patients from a Neurological Practice Treated with Ginkgo:Study objective: Effectiveness testing of a ginkgo biloba special extract an improvement of well-being and cerebral functional capacity. .Design: Randomized, double-blind placebocontrolled trial for 12 weeks.Patients: 50 outpatients with degenerative and vascular dementia.Therapy: 3 tablets of 50 mg ginkgo biloba special extract daily or 3 placebo tablets.End points: Psychometric tests and judgement scales.Results: Premature discontinuations in 3 patients from the placebo group and 5 patients from the active treatment group; undesired drug effects under placebo treatment once, under active treatment twice. Significant differences between both groups after 12 weeks for 7 out of 11 typical symptoms of cerebral insufficiency in favour of the active treatment group; active treatment group significantly faster in carrying out the figure connection test after 6 and 12 weeks; in the syndrome short test the comparison of placebo and active treatment group as well as the treatment course shows significantly better results in the active treatment group.Conclusion: The treatment with ginkgo biloba special extract resulted in an improvement in the cerebral functional capacity of typical symptoms of cerebral insufficiency in patients with degenerative and vascular dementia.

Keyword(s): Ginkgo biloba

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