Immunological and hematological changes during balneotherapy in Badgastein.(Immunologische und hämatologische Veränderungen während einer Badekur in Badgastein.)
Journal/Book: Z Phys Med Baln Med Klim. 1990; 19:300-305.. 1990;
Abstract: Our earlier investigations dealing with DNA-repair and natural killer cells indicated that immunological reactions are activated by spa treatment in Badgastein. In patients with rheumatic diseases urinary neopterin excretion increased and indicated an activation of monocytes and macrophages. Determinations of blood cell counts with modern Coulter-counters at the beginning and at the end of spa treatment confirmed a decrease of leucocyte number and an increase of hemoglobin concentration. Measurement of cytokine concentrations like TNF-alpha and IFN-gamma in serum of patients with ankylosing spondylitis and patients with rheumatoid arthritis revealed a slight increase of serum concentrations caused by spa treatment.