Preventive effect of an E. coli-filtrate (Colobiogen) in polymorphous light eruption

Author(s): Heppeler, M., Ruzicka, T.

Journal/Book: British Journal of Dermatology. 1989; 121: 29-233.

Abstract: During the administration of Colibiogen®, a commercially available E. coli-filtrate, there was a significant (P < o-oI) increase of the test dose of UVA necessary to elicit skin lesions in nine patients with polymorphous light eruptions. Control tests performed in the same manner without the drug indicate that this was due to treatment. Colibiogenv appears to be of value in the treatment of polymorphous light eruption (PLE).

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