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January 2022

Gezielte konservative Therapie der akuten Sinusitis in der HNO-Praxis

Journal/Book: Therapiewoche. 1985; 35: 4024-4028.

Abstract: 90 patients suffering from objectified acute sinusitis were treated with three different therapeutical concepts; the treatment groups were allocated by randomisation in a single blind study. 30 patients were treated with an antibiotic medication alone; 30 patients received the antibiotic plus an immunostimulant drug; 30 patients were treated with the antibiotic plus a secretolytic medication. In both treatment groups (antibiotic plus additional medication) the results were significantly better than those in the antibiotic group based on: clinical symptoms, the global therapeutic success and roentgenographic findings. Furthermore the global therapeutical success of the antibiotic plus immunostimulant therapy was better than the antibiotic plus secretolytic drug treatment. The therapeutic concept of optimizing the antibiotic effect by supporting the host defence system could be demonstrated in this investigation.

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