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November 2024

Inhibition of Monoamine Oxidase by Hypericin

Author(s): Katsumata, Y., Oya, M., Bladt, S., Wagner, H.

Journal/Book: Planta medica. 1984;

Abstract: Hypericin from Hypericum perforatum was found to inhibit in vitro type A and B monoamine oxidase (MAO's) prepared by treating rat brain milochondria with selective inhibitors. The inhibition of type A MAO by hypericin was higher than that of type B MAO. The inhibition was almost irreversible tot both MAO typcs.


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