Thymus extract therapy in immunodepressed patients with malignancies and herpes virus infections

Author(s): Bernengo, M., Cordero, D. , Montezemolo, L, Del, P. , A, Saitta, M., Nicola, P.

Journal/Book: Thymus. 1980; 2: 41-48.

Abstract: Twelve immunodepressed children with malignancies and herpes virus infections were treated with a: thymus extract (TP-1). In all but one a good and sometimes dramatical clinical response was observed. There was in 5 patients an increase of peripheral T lymphocytes, in 7 of the total peripheral lymphocytes, in 6 of granulocytes, and in 2 of erythrocytes and platelets.The absence of an increase in E-rosette forming cells after in vitro incubation with TP-1, prior to treatment, and the rapid effectiveness of therapy suggest that the hormone acts an already differentiated T lymphocytes or influences the interferon production, as observed in mice.

Keyword(s): herpes virus infection

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