Capillary Stress Response and Species.* (21865)

Journal/Book: Reprinted from PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 1955 v89 528-533. 1955;

Abstract: From the Department of Pediatrics Creighton University School of Medicine Omaha Nebr. * This work represents part of a project supported by the Cardiovascular Section of the Division of Research Grants of the U. S. Public Health Service and by Creighton University School of Medicine. Summary 1. Changes in capillary resistance resulting from 8 forms of stress were studied on dogs guinea pigs and rabbits in order to integrate previous similar studies on the human being and the rat. 2. Immediate and late responses were investigated and essentially the same patterns of response found as previously described. A comparison of the results obtained on all five species studied shows that practically every pattern may occur in each of the 5 species yet in each species certain patters predominate. Thus the species difference resolves itself into a difference in the incidence in which the various patters occur. 3. Knowledge of the capillary stress response is indispensable in any clinical or experimental study in which capillary resistance is measured. 4. An evaluation of the five species is given as to their suitableness to and relative value in capillary resistance studies.

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