Salicylates and Rheumatic Disease

Journal/Book: ARTHRITIS AND RHEUMATISM Vol. 9 No. 2 (APRIL) 1966 342-347. 1966;

Abstract: From the Departments of the Robert B. Brigham and Peter Bent Brigham Hospitals Bosten Mass.THEODORE B. BAYLES M.D.: Director of Research and Visiting Physican Robert B. Brigham Hospital; Senior Associate in Medicine Peter Bent Brigham Hospital; Assistant Clinical Professor of Medicine Harvard Medical School Bosten Mass. B ITTER MATERIAL from the barks and roots of various bushes and trees has been used in medicine since the days of Hippocrates Celsus Pliny Dioscorides and Galen. The bark of the willow (Latin Salix) hence old English sallow first emerged on the Anglo-American medical scene in 1763 when the Reverend Edward Stone in a communication to the Royal Society revealed to the developing scientiflc world in England the fact that the bark of the willow was useful. He stated As this tree delights in a moist or wet soil, where agues chiefly abound, the general maxim that many natural maladies carry their cures along with them or that their remedies lie not far from their causes was so very apposite to this particular case that I could not help applying it; and that this might be the intention of Providence here, I must own, had some little weight with me. He concluded that this bark was useful in the treatment of such human ills as agues fevers abscesses and fluxes. Therefore the willow bark was used primarily as an antipyretic and only by accident in rheumatism... schö

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