Planta Med. 2003 Apr; 69(4): 382-4.

First isolation of a symmetrical glycosylated methylene bisflavonoid.

De Oliveira DB, de Almeida AP, De B A SimÃµes GL, Auvin C, Kaiser CR, Costa SS.

Blutaparon portulacoides (St. Hil.) Mears (= Philoxerus portulacoides St. Hil.) (Amaranthaceae) is a species occurring in the Brazilian coast in two botanical varieties. The chemical study of an ethanolic extract led to the isolation of spinacetin 3- O-robinobioside as well as an unique glycosylated pseudo-dimeric flavonoid identified as 8,8""-methylene bis(spinacetin 3- O-robinobioside) mainly by NMR analyses (1H, 1H- 1H COSY, 13C, HMQC, HMBC) and MALDI-TOF mass spectrometry.