Planta Med. 2003 Mar; 69(3): 274-7.

Antibacterial activity and chemical composition of essential oil of Chrysanthemum boreale.

Kim KJ, Kim YH, Yu HH, Jeong SI, Cha JD, Kil BS, You YO.

The essential oil of Chrysanthemum boreale Makino was analyzed by means of GC and GC-MS. Eighty-seven constituents were identified, representing 94.13 % of the total oil and the major components were camphor, alpha-thujone, cis-chrysanthenol, 1,8-cineole, alpha-pinene, and beta-caryophyllene. Furthermore, the essential oil exhibited antibacterial activity (MIC, more than 800 microg/mL versus 0.125 microg/mL for ampicillin) after it was tested against 6 Gram(+) bacteria and 8 Gram(-) bacteria.