Eksp Klin Farmakol. 2002 Nov-Dec; 65(6): 28-31.

[Cerebrovascular and renal actions of bilobil and its effect on the metal ligand homeostasis (clinico-experimental study]

Limanova OA, Shtrygol' SIu, Gromova OA, Andreev AV.

Pharmacology and Clinical Pharmacology Department, Ivanovo State Medical Academy, pr. Engel'sa 8, Ivanovo, 153462 Russia.

The tests on rats with common carotid artery occlusion showed that bilobil increases the cerebral blood flow and decreases brain edema, thus decreasing the loss of experimental animals. The drug also increases the blood circulation and improves the excretory function of kidneys. Under clinical conditions, bilobil increases the cerebral blood flow, normalizes the metal ligand homeostasis, and improves the antioxidant status in children with early forms of cerebrovascular disease (neurocirculate distonia) and attention deficit hyperactivity syndrome.