Phytomedicine. 2002 Dec; 9(8): 731-3.

Evaluation of anti-pyretic potential of Ficus racemosa bark.

Rao RB, Anupama K, Swaroop KR, Murugesan T, Pal M, Mandal SC.

Department of Pharmaceutical Technology, Jadavpur University, Calcutta, India.

A study was carried out to evaluate the anti-pyretic effect of a methanol extract of stem bark of Ficus racemosa Linn. (MEFR) on normal body temperature and yeast-induced pyrexia in albino rats. A yeast suspension (10 ml/kg body wt.) increased rectal temperature 19 h after subcutaneous injection. The MEFR, at doses of 100, 200 and 300 mg/kg body wt. p.o., showed significant dose-dependent reduction in normal body temperature and yeast-provoked elevated temperature. The effect extended up to 5 h after drug administration. The anti-pyretic effect of MEFR was comparable to that of paracetamol (150 mg/kg body wt., p.o.), a standard anti-pyretic agent.