Zhongguo Zhong Xi Yi Jie He Za Zhi. 2002 Jan; 22(1): 30-2.

[Clinical observation on colquhounia root tablet in treating lipid metabolism disturbance secondary to nephrotic syndrome]

Wu XL, Li JB, Mo SL.

TCM Department of First Affiliated Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou 510080.

OBJECTIVE: To study the effect of Colquhounia root tablet (CRT) in treating nephrotic syndrome with sequential lipid metabolism disorder (NS-LMD). METHODS: The 96 patients with NS-LMD were randomly divided into two groups, the 60 cases in the treated group treated with CRT and the 36 cases in the control group treated with hormone or cytotoxic medicine. The curative effect and the related indexes were determined before and after treatment. RESULTS: After six months treatment, the general effective rate in the treated group was 88. 33%, which was markedly higher than that in the control group (69.44%, P < 0.05). The levels of the treated group in ameliorating lipid metabolism disorder and renal dysfunction were also higher than those in the control group (P < 0.05). CONCLUSION: CRT could improve NS-LMD, improve renal function, eliminate urinary protein and increase plasma albumin. It is highly effective with low toxicity and safe.