Zhongguo Zhong Xi Yi Jie He Za Zhi. 2002 Aug; 22(8): 584-6.

[Clinical observation on effect of yishen jiedu recipe in retarding the course of chronic renal failure]

Chen SH, Ban ZP, Cao JL.

Guizhou Provincial Zunyi Hospital, Guizhou 563002.

OBJECTIVE: To observe the effect of Yishen Jiedu Recipe (YSJDR) in retarding the course of chronic renal failure (CRF). METHODS: Forty-five patients were divided into two groups, the 22 patients in Group A were treated with low-protein diet and blood pressure controlling therapy only, while the 23 patients in Group B were treated with additional YSJDR. The time (month) for doubling serum creatinine (SCr) level was taken to evaluate the speed of CRF progression. RESULTS: In Group A, the time for SCr increased from 288.4 +/- 96.7 mumol/L to 586.3 +/- 251.3 mumol/L was 16.7 +/- 5.1 months, while in Group B the time for SCr increased from 291.2 +/- 101.2 mumol/L to 589.6 +/- 257.5 mumol/L was 28.2 +/- 8.7 months. Comparison between the two groups showed significant difference (P < 0.05). CONCLUSION: On the basis of low-protein diet and blood pressure controlling therapy, the additional treatment of YSJDR could markedly retard the progression speed of CRF.