Phytother Res. 2002 Nov; 16(7): 700-2.

Anti-stress and anti-fatigue effect of fermented rice bran.

Kim KM, Yu KW, Kang DH, Suh HJ.

School of Food Biotechnology, Woosong University, Daejeon 300-718, Korea.

The anti-stress and anti-fatigue effects of a hot water extract of fermented rice bran (FRB) were investigated with Saccharomyces cerevisae IFO 2346 on rats or mice. Oral administration (1 g/kg/day) of a hot water extract of FRB inhibited major changes in weight of the adrenal, thymus, spleen and thyroid, showing the anti-stress effect. A hot water extract of FRB also inhibited the increase of GPT and LDH activity, cholesterol and serum glucose levels. Administration (1 g/kg/day) for 2 weeks significantly prolonged the swimming time, resulting in an increase of the anti-fatigue effect. From these results, it can be considered that FRB has an anti-stress and anti-fatigue effect.Copyright 2002 John Wiley & Sons, Ltd.