Fitoterapia. 2002 Oct; 73(6): 451-5.

Hypolipidemic activity of Acorus calamus L. in rats.

Parab RS, Mengi SA.

CU Shah College of Pharmacy, SNDT Women's University, Santacruz (West), Mumbai 400 049, Maharashtra, India.

The rhizomes of Acorus calamus are empirically used in the treatment of a wide variety of human diseases. Administration of the 50% ethanolic extract (100 and 200 mg/kg) as well as saponins (10 mg/kg) isolated from the extract demonstrated significant hypolipidemic activity. On the contrary, the aqueous extract showed hypolipidemic activity only at a dose of 200 mg/kg.Copyright 2002 Elsevier Science B.V.