J Tradit Chin Med. 2002 Jun; 22(2): 93-8.

Clinical observation on the therapeutic effects of zhongyan-2 recipe in treating 29 HIV-infected and AIDS patients.

Wang J, Yu Z, Li G, Zhang Y, Guan C, Lu W.

Institute of Basic Theory, China Academy of Traditional Chinese Medicine, 18 Beixincang, Dongzhimennei, Beijing 100700.

OBJECTIVE: To investigate the efficacy of Zhongyan-2 Recipe (ZY-2), a recipe consisting of Chinese herbal medicine. METHODS: Twenty-nine HIV-infected patients were treated with ZY-2 for 3 months as one treatment course; and viral load, immune function and symptoms-signs were determined before and after treatment. RESULTS: After treatment, the absolute values of CD4 were elevated in 8 cases, and lowered in 14 cases, 7 cases were not changed; the ratio of CD4/CD8 were elevated in 2 cases, lowered in 1 case, 16 of them were not changed obviously. The CD4 and CD4/CD8 ratio were elevated simultaneously in 2 cases. Neopterin lowered in 4 cases, elevated in 11 cases, and not changed in 1 case. Viral load (VL) was lowered in 6 cases, elevated in 8 cases and not changed in 2 cases. The total effective rate was 42.28% on the basis of comprehensive assessment of VL, immune function, body weight and symptoms-signs. CONCLUSION: ZY-2 is an effective Chinese recipe in treating HIV-infected patients.