J Asian Nat Prod Res. 2002 Sep; 4(3): 189-96.

The active constituents from Gualou-xiebai-baijiu-tang part I: active saponins.

He XJ, Qiu F, Shoyama Y, Tanaka H, Yao XS.

Department of Natural Products Chemistry, Shenyang Pharmaceutical University, China.

Two new steroidal saponins and a new triterpenoidal saponin, together with nine known steroidal saponins, were isolated from "Gualou-xiebai-baijiu-tang" consisting of Fructus trichosanthis and Bulbus allii macrostemi. The structures of the three new compounds were determined as 3-O-beta-D-galactopyranosyl-hederagenin 28-O-beta-D-xylopyranosyl (1-->6)-beta-D-galactopyranosyl ester (1), spirost 25(27)-ene-2beta,3beta-diol-3-O-beta-D-glucopyranosyl (1-->2)-beta-D-galactopyranoside (2) and 26-O-beta-D-glucopyranosyl-22alpha-hydroxy-5beta-furost-25(27)-ene-1beta,3beta,6beta,26-tetraol-3-O-beta-D-galactopyranoside (3), respectively, by means of chemical evidences and spectral analysis.