Planta Med. 2002 Jun; 68(6): 568-9.

A new diterpene from Tanaecium jaroba.

Mitaine-Offer AC, Sauvain M, Deharo E, MuÃ±oz V, ZÃ¨ches-Hanrot M.

One new diterpene, 2 alpha-hydroxy-12beta-hydroxy-isopimara-8(14), 15-diene, and six known compounds as triterpenes, sterols and fatty acid, were isolated from the stem bark of Tanaecium jaroba (Bignoniaceae), a Bolivian plant used in traditional medicine. Their structures were established mainly by 1D and 2D NMR (COSY, HMQC, HMBC, ROESY) and their antiplasmodial activities were evaluated in vitro against Plasmodium falciparum.