Nat Prod Lett. 2002 Jun; 16(3): 149-53.

Three new hydroxylated serratidine alkaloids from Huperzia serrata.

Tan CH, Ma XQ, Jiang SH, Zhu DY.

Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences.

A known compound, serratidine (1), along with three hydroxylated serratidine alkaloids, 6alpha-hydroxyserrati dine (2), 4alpha-hydroxyserratidine (3) and 4alpha,6alpha-dihydroxyserratidine (4) were isolated from the CHCl3 fraction of basic materials of whole plant of the Chinese medicinal herb Huperzia serrata. The relative configurations of the above compounds were determined based on 2D NMR studies.