Phytomedicine. 2002 Apr; 9(3): 202-6.

Studies on the psychopharmacological activities of Rumex nepalensis Spreng. root extract in rats and mice.

Ghosh L, Arunachalam G, Murugesan T, Pal M, Saha BP.

Department of Pharmaceutical Technology, Jadavpur University, Calcutta, India.

The methanol extract of Rumex nepalensis Spreng. (Family - Polygonaceae) was assessed for different psychopharmacological activities in rats and mice by evaluation of general behaviour, exploratory behaviour, muscle relaxant activity and phenobarbitone sodium-induced sleeping time. The extract at doses 200 mg/kg and above exhibited a reduction in spontaneous activity (general behavioural profile), a decrease in exploratory behavioural pattern in the Y-maze and Head-dip tests, a reduction in muscle relaxant activity in rotarod, 30 degrees inclined screen and traction tests, and also potentiated phenobarbitone sodium-induced sleeping time.