Fitoterapia. 2002 Apr; 73(2): 111-5.

Preliminary study on antifertility activity of Calotropis procera roots in female rats.

Kamath JV, Rana AC.

Department of Pharmacology, Krupanidhi College of Pharmacy, Sarjapur Road, Kormanagala, Bangalore 560 034, India. [email protected]

The effect of ethanolic extract of the roots of Calotropis procera has been studied in albino rats to explore its antifertility and hormonal activities. A strong antiimplantation (inhibition 100%) and uterotropic activity was observed at the dose level of 250 mg/kg (1/4 of LD(50)). No antiestrogenic activity could be detected.