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Nat Prod Lett. 2002 Feb; 16(1): 33-7.

Diterpenes from Sideritis trojana.

Topçu G, Gören AC, Kiliç T, Yildiz YK, T�men G.

University of Istanbul, Faculty of Pharmacy, Beyazit-Istanbul, Turkey.

Six known ent-kaurene, a new ent-kaurane and a new pimarane diterpenes were isolated from Sideritis trojana. The structures of new compounds were determined as ent-7alpha-15beta,16beta-epoxykaurane (1), and ent-2alpha-hydroxy-8(14),15-pimaradiene (2) along with the known compounds siderol (3), sideridiol (4), 7-epicandicandiol (5), isocandol B (6), candol A acetate (7) ent-7alpha-acetoxykaur-15-ene (8) by IR, 1D and 2D NMR techniques and HRMS.


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