Phytother Res. 2002 Mar; 16 Suppl 1(): S75-7.

Antiinflammatory property of the leaves of Gongronema latifolium.

Morebise O, Fafunso MA, Makinde JM, Olajide OA, Awe EO.

Department of Biochemistry, College of Health Sciences, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.

An aqueous extract of the dried leaves of Gongronema latifolium was studied for its antiinflammatory activity. The extract significantly (p < 0.05) inhibited carrageenan-induced rat paw oedema, carrageen-induced leucocyte migration in rats and dye leakage induced by intraperitoneal injection of acetic acid in mice. These results demonstrate the antiinflammatory property of G. latifolium.Copyright 2002 John Wiley & Sons, Ltd.