Fitoterapia. 2002 Feb; 73(1): 28-31.

Diuretic, laxative and toxicity studies of Cocculus hirsutus aerial parts.

Ganapaty S, Dash GK, Subburaju T, Suresh P.

Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam, A.P. 530003, India. [email protected]

The aqueous extract of the Cocculus hirsutus aerial parts (100 and 200 mg/kg, p.o.) showed significant diuretic activity and laxative effect in rats. The acute toxicity, orally evaluated in mice, was found to be higher than 3000 mg/kg.