Harefuah. 2002 Jan; 141(1): 61-6, 125.

[Soy and phytoestrogens consumption and health policy hesitation or certitude]

Nitzan-Kaluski D, Stern F, Kachel J, Leventhal A.

Department of Nutrition, Ministry of Health, Sackler Faculty of Medicine, Tel Aviv University.

Soy and phytoestrogens are controversial as to their beneficial effects on health and the prevention of disease. To date, dietary recommendations in Israel do not specify a diet rich in soy and phytoestrogens. In order to establish a policy on this issue, we carried out a comprehensive, updated review of the relevant scientific literature. Data on the role of these substances in the primary and secondary prevention of cancer are limited. As yet, there is no conclusive evidence on the efficacy of phytoestrogens and soy in the prevention of osteoporosis. Their effect on fertility in animals and humans is still unclear. There are no data on the long-term risks or benefits of using soy-based formulae in infancy. Therefore, for those who cannot be breast-fed, cow-milk based formulae are recommended. Currently, the most supportive evidence for health benefits of soy can be found in studies on the prevention of cardiovascular diseases.