Phytother Res. 2002 Feb; 16(1): 91-3.

Effect of the antiulcer polysaccharide fraction from Bupleurum falcatum L. on the healing of gastric ulcer induced by acetic acid in rats.

Matsumoto T, Sun XB, Hanawa T, Kodaira H, Ishii K, Yamada H.

Oriental Medicine Research Centre, The Kitasato Institute, Tokyo, Japan.

An antiulcer polysaccharide fraction (BR-2) from Bupleurum falcatum L. was examined for its effect on the healing of chronic ulcers induced by acetic acid in rats. When BR-2 was administered orally to the rats, it was shown to be effective in the healing of acetic acid-induced chronic ulcer. This result suggests that the use of herbal prescriptions containing B. falcatum L. may prove useful for the treatment of peptic ulcers.Copyright 2002 John Wiley & Sons, Ltd.