Zhongguo Zhong Xi Yi Jie He Za Zhi. 2001 Mar; 21(3): 171-3.

[Effect of huangqi zengmian powder on interstitial response in patients with esophageal cancer at peri-operational period]

Gao XP, Zhao WX, Zhang ZL.

Department of Pathology, Xinxiang Medical College, Henan 453003.

OBJECTIVE: To observe the effect of Huangqi Zengmian Powder (HQZMP) on interstitial response of esophageal cancer at peri-operational period. METHODS: Thirty-seven patients of esophageal cancer were treated with HQZMP for 4 weeks peri-operationally. The pathological interstitial changes (including mastocyte, microvessels and lymphocytic response) in resected esophageal cancer sample were observed using toluidine blue stain. RESULTS: As compared with the non-HQZMP treated control group, quantity of interstitial mastocyte, focal lymphocytic aggregation and interstitial microvessel damage in the HQZMP treated group were more obvious (P < 0.01). CONCLUSION: HQZMP could improve the immune function of esophageal patients in peri-operational period.