Zhongguo Zhong Xi Yi Jie He Za Zhi. 2001 Oct; 21(10): 739-41.

[Effect of tuoli xiaodu powder on cell-mediated immunofunction in liver carcinoma patients before and after surgical operation]

Li HH, Liang JX, Chen JS.

Memorial Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou 510120.

OBJECTIVE: To explore the regulatory effect of Tuoli Xiaodu Powder (TLXDP) on cell mediated immunofunction (T-lymphocytes subsets) in liver carcinoma patients. METHODS: Thirty-eight patients with operable liver carcinoma were divided randomly into 2 groups. TLXDP was given to the 20 cases in Group I before and 7 days after surgical operation, but not given to the 18 cases in Group II. T-lymphocyte subsets (CD3, CD4 and CD8 by monoclonal antibody labelled direct immune rosette method) and liver function, aspartate aminotransferase (AST), alanine transaminase (ALT), direct and indirect bilirubin (DBIL and IBIL) were determined before and after treatment. RESULTS: T-lymphocyte subsets elevated and liver function enhanced significantly in Group I after treatment, but unchanged in Group II. CONCLUSION: Administration of TLXDP before and after surgical operation could enhance the cell-mediated immunofunction and improve the liver function significantly in patients with liver carcinoma.