Z Naturforsch [C]. 2001 Nov-Dec; 56(11-12): 939-42.

Phytochemical and pharmacological analysis of Bauhinia microstachya (Raddi) Macbr. (Leguminosae).

Meyre-Silva C, Yunes RA, Delle Monache F, Santos AR, Schmeling LO, Gadotti VM, Liz F, Cechinel-Filho V.

Departamento de QuÃmica, Universidade Federal de Santa Catarina UFSC, FlorianÃ³polis, SC, Brazil.

This paper describes the isolation of four phytoconstituents from the leaves of Bauhinia microstachya, a Brazilian medicinal plant used in folk medicine for the treatment of several ailments. Based on spectroscopic evidence, these compounds were identified as methyl gallate (1), kaempferol 3-O-rhamnosyl (2), quercitrin (3) and myricitrin (4). The crude methanolic extract and two compounds (3 and 4) were tested as analgesic using the writhing test in mice. The extract and compound 3 caused potent and dose-related analgesic effects, confirming the popular use of this plant for the treatment dolorous processes.