Klin Med (Mosk). 2001 ; 79(11): 52-4.

[Galstena efficacy in patients with biliary dyskinesia, chronic cholecystitis and cholelithiasis]

Grigor'eva IN, Shabalin AV, Tikhonov AV, Moiseenko EE, Ragino IuI.

The response of inflammation, bile secretion, lipid metabolism, LDL sensitivity to oxidation was studied in patients with bile duct dyskinesia (BDD), chronic cholecystitis (CC) and cholelithiasis (CL) before and after a course of therapy with galstena. The treatment improved general condition in 90% of the patients, dyspeptic symptoms relieved or stopped. Galstena relieved general or local inflammation, reduced mean levels of total cholesterol and LDL cholesterol, raised HDL cholesterol. In patients with BDD and cholelithiasis galstena did not change normal sensitivity of LDL to oxidation. A galstena course in BDD and CC patients significantly diminished bile lithogenicity and improved gall bladder contractility.