Therapie. 2001 Sep-Oct; 56(5): 607-11.

[Coronary disease protective factors: antioxidant effect of olive oil]

Covas MI, FitÃ³ M, Marrugat J, MirÃ³ E, FarrÃ© M, de la Torre R, Gimeno E, LÃ³pez-Sabater MC, Lamuela-RaventÃ³s R, de la Torre-Boronat MC.

Unitat de LÃpids i Epidemiologia Cardiovascular, Institut Municipal d'InvestigaciÃ³ MÃ¨dica (IMIM), Carrer Dr. Aiguader, 80, 08003 Barcelona, Espagne.

Alongside the French paradox, the REGICOR Study (Girona, Spain) has shown another paradox in the Mediterranean area: a high prevalence of cardiovascular risk factors with low incidence of myocardial infarction in the population of Girona, Spain. The antioxidant effects associated with olive oil consumption could explain part of this 'Mediterranean Paradox'. Virgin olive oils processed by two centrifugation phases and with low fruit ripeness have the highest levels of antioxidant content. The total content of phenolic compounds (PC) from virgin olive oil could delay LDL oxidation. The content and nature of olive oil PC have a high influence in the antioxidant capacity of an olive oil. PC from diet could bind human LDL in non-supplemented volunteers. PC from virgin olive oil could bind LDL and tyrosol is bioavailable in humans from ingestion of virgin olive oil in its natural form.