Fiziol Zh. 2001 ; 47(5): 77-81.

[Effect of hypergravity on the oxidative-antioxidative status of rats.]

Karbashevs'ka NIa, OliÄnyk SA, Bilokin' IuM, BaraboÄ VA, Hrynevych IuP.

Medical Institute of Ukrainian Assiciation of Folk Medicine, Kiev.

The adaptogenic and antioxidant properties of new Ukrainian plant drug "Poliphytolum" was investigated on the model of stress, which was caused of hypergravitation 2 and 5 N.m2/kg2 action. It was established that hypergravitation makes typical stressory disturbances in oxidative homeostasis. The normalization action of "Polyphytolum" on lipid peroxidation is more strong in liver, spleen and blood, and less more--in brain. It may be caused of low level the drug in the brain tissue.