Planta Med. 2001 Nov; 67(8): 766-7.

Anti-thrombosis effect of paeoniflorin: evaluated in a photochemical reaction thrombosis model in vivo.

Ye J, Duan H, Yang X, Yan W, Zheng X.

Department of Biomedical Engineering, Zhejiang University, Hangzhou City, China.

In a photochemical reaction microvessel thrombosis model, the anti-thrombotic effect of PT was evaluated and the results showed that PF could significantly prolong thromobosis time. The anti-thrombotic effect of PF may relate to the inhibition of arachidonic acid metabolism, the increase of t-PA activity, and the protective effect against free radical.