Nutr Rev. 2001 Nov; 59(11): 372-4.

Preventive role of dietary fiber in gastric cardia cancers.

Roth J, Mobarhan S.

Department of Medicine at the Loyola University Medical Center, Maywood, IL 60153, USA.

The incidence of adenocarcinoma of the esophagus and gastric cardia is increasing. Many factors are presumed to be associated: symptoms of gastroesophageal reflux disease, tobacco use, alcohol consumption, dietary factors, and obesity. A recent large population-based case-control study evaluated the association between dietary fiber intake and cancers of the gastric cardia and esophagus. This interesting study indicated that high intake of cereal fiber may significantly decrease the risk of gastric cardia cancer. More research is needed on this topic in the hope that dietary intake may decrease the incidence of these cancers.