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November 2024

Fundam Clin Pharmacol. 2001 Aug; 15(4): 265-8.

Aphrodisiac evaluation in non-copulator male rats after chronic administration of Eurycoma longifolia Jack.

Ang HH, Ngai TH.

School of Pharmaceutical Sciences, University of Science Malaysia, Minden, 11800, Penang, Malaysia.

The aphrodisiac effect of Eurycoma longifolia Jack (0.5 g/kg) was evaluated in noncopulator male rats using an electrical cage. Fractions of E. longifolia Jack decreased the hesitation time of noncopulator male rats, throughout the investigation period. Furthermore, it possessed a transient increase in the percentage of the male rats responding to the right choice, more than 50% of the male rats scored "right choice" after 3 weeks post-treatment and the effect became more prominent after 8 weeks post-treatment (only 40-50% of the control male rats responded to the right choice) using the electrical copulation cage. Hence, this study lends further support to the use of the plant by indigenous populations as a traditional medicine for its aphrodisiac property.


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