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December 2024

Pharmazie. 2001 Jun; 56(6): 506-8.

The effects of aqueous extracts of Desmodium gangeticum DC. (Leguminosae) on the central nervous system.

Jabbar S, Khan MT, Choudhuri MS.

Pharmacology Research Lab., Faculty of Basic Medical and Pharmaceutical Sciences, University of Science and Technology Chittagong, Foy's Lake, Chittagong, Bangladesh.

The aqueous extract of Desmodium gangeticum DC. (Leguminosae) showed no analgesic activity in the hot plate method, but it showed severe anti-writhing activity in the acetic acid-induced abdominal writhing assay. It exhibited moderate central nervous system depressant activity in the spontaneous motor activity, hole cross, and open field tests and hole board tests. The effects of this extract on locomotion were compared with some standard CNS drugs.


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