Fitoterapia. 2001 Jan; 72(1): 12-21.

Anthelmintic activity of crude aqueous extract of Nauclea latifolia stem bark against ovine nematodes.

Onyeyili PA, Nwosu CO, Amin JD, Jibike JI.

Department of Veterinary Physiology and Pharmacology, Maiduguri, Nigeria. [email protected]

The anthelmintic efficacy of Nauclea latifolia stem bark aqueous extract was studied in sheep with natural acute/sub-acute parasitic gastro-enteritis due primarily to mixed nematode species. Graded doses of the extract (400, 800 and 1600 mg/kg, p.o for 5 consecutive days) significantly reduced faecal egg counts in infected animals. The percentage reduction (93.8%) by 1600 mg/kg of the extract was comparable to that of 5 mg/kg of albendazole (94.1%). The administration of the extract resulted in improved haemoglobin and leucocytosis values in worm-infected sheep.