Zhongguo Zhong Yao Za Zhi. 2000 Mar; 25(3): 175-8.

[Effect of chuanwu and baishao used separately or in combination on adjuvant arthritis in rats]

Xue L, Zhang HY, Qin L, Wang XC, Wang L.

Shandong University of Traditional Chinese Medicine, Jinan 250014, Shandong, China.

OBJECTIVE: To study the effect of Chuanwu(Aconitum carmichaeli) and Baishao(Paeonia lactiflora) used separately or in combination on the adjuvant arthritis in rats. METHOD: Chuanwu-Baishao decoctions of different proportions were orally administered to three different rat models with adjuvant arthritis to observe the preventing and curing actions on the primary and secondary adjuvant arthritis in rats. RESULT: The curing action on the primary adjuvant arthritis appeared the same whether the two ingredients were used separately or in combination, while on the secondary adjuvant arthritis the combination, produced significant preventing effect. Chuanwu was proved weaker in action when used alone Chuanwu and Baishao were very efficacious in curing adjuvant arthritics when used in combination other than separately. CONCLUSION: In preventing and curing the secondary adjuvant arthritis in rats Chuanwu and Baishao work better in combination.