Zhongguo Zhong Xi Yi Jie He Za Zhi. 2000 Oct; 20(10): 729-30.

[Clinical study on Shenning Mixture in treating IgA nephropathy]

Bo S, Ju J, Chu D.

Yuhuangding Hospital, Yantai City, Shandong 264000.

OBJECTIVE: To study the clinical therapeutic effect of Shenning Mixture (SNM) in treating IgA nephropathy. METHODS: Patients were treated separately with SNM or prednisone by randomized grouping. The criteria, including clinical symptoms, signs, hematuria, albuminuria and immune globulin were observed. RESULTS: The total effective rate and the complete remission rate in the SNM group were 97.1% and 45.7% respectively, while in the control group, they were 37.1% and 8.6% respectively. Comparison of the two groups showed that the therapeutic effect in the former was better than that in the latter significantly, P < 0.01. The hematuria and albuminuria extenuated and serum IgA lowered more significantly in the SNM group than those in the control group (P < 0.05, P < 0.01). CONCLUSION: SNM has obvious therapeutic effect on the hematuria and albuminuria in treating IgA nephropathy.