Fitoterapia. 2000 Sep; 71(5): 562-3.

Antinociceptive activity of Euphorbia heterophylla roots.

Vamsidhar I, Mohammed AH, Nataraj B, Madhusudana Rao C, Ramesh M.

K.M. College of Pharmacy, Madurai 625107, India.

Following an identified use of the plant as analgesic in traditional medicine, the hexane, chloroform and ethyl acetate extracts of Euphorbia heterophylla root have been tested for antinociceptive activity in rats. All extracts showed significant effects at doses of 150-300 mg/kg i.p.