Pharmazie. 2000 Nov; 55(11): 848-9.

New stilbene carboxylic acid from Convolvulus hystrix.

Dawidar AM, Ezmiriy ST, Abdel-Mogib M, el-Dessouki Y, Angawi RF.

Chemistry Department, Faculty of Science, Mansoura University, Mansoura, Egypt.

Convolvulus hystrix Vahl. (family Convolvulaceae) is a common wild plant growing in the kingdom of Saudi Arabia. It is used in traditional medicine. Our study resulted in the isolation and structural elucidation of ten natural products from which a stilbene carboxylic acid was isolated for the first time as a new natural product. The isolated products are mainly shikimates in addition to two sterols; beta-sitosterol and stigmasterol, as well as one triterpenoid, oleanolic acid. The shikimate products are vanillin, vanillic acid, syringic acid, ferulic acid, isoferulic acid, isoscopoletin and the new stilbene derivative. The structures were elucidated on the basis of spectral data from 400 MHz 1H NMR, MS, IR and UV. The biogenesis of the new stilbene is discussed.