Phytother Res. 2000 Nov; 14(7): 552-4.

Cytotoxic activity of Agave intermixta L. (Agavaceae) and Cissus sicyoides L. (Vitaceae).

SÃ¡enz MT, Garcia MD, Quilez A, Ahumada MC.

Laboratory of Pharmacognosy, Faculty of Pharmacy, University of Seville, s/n, 41012 - Seville, Spain. [email protected]

The cytostatic activities of Agave intermixta L. (Agavaceae) and Cissus sicyoides L. (Vitaceae) have been determined. In the antimitotic assay, Agave intermixta L. showed complete inhibition of cell division at 24 h of treatment. Both species showed a moderate cytostatic activity against HEp-2 cells, Cissus sicyoides L. being the most active species.Copyright 2000 John Wiley & Sons, Ltd.