Phytochemistry. 2000 Aug; 54(8): 767-70.

Diterpenoids from the roots of Croton macrostachys.

Kapingu MC, Guillaume D, Mbwambo ZH, Moshi MJ, Uliso FC, Mahunnah RL.

Institute of Traditional Medicine, Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania. [email protected]

Three novel diterpenoids have been isolated from the roots of Croton macrostachys. The structure and stereochemistry of the compounds have been unambiguously settled as neoclerodan-5,10-en-19,6beta;20,12-diolide, 3alpha, 19-dihydroxytrachylobane, and 3alpha,18,19-trihydroxytrachylobane from detailed spectroscopic evidence.