Phytomedicine. 2000 Jan; 6(6): 474-6.

Arnebins and antimicrobial activities of Arnebia hispidissima DC. cell cultures.

Jain SC, Singh B, Jain R.

Department of Botany, University of Rajasthan, Jaipur, India.

The whole plant of Arnebia hispidissima DC. (Boraginaceae) is used for the treatment of tongue and throat ailments in Indian traditional medicine. The present paper deals with the plants phytochemical constituents, the arnebins, and antimicrobial activities of its root extract. The antimicrobial activities were tested against Gram-positive and Gram-negative bacteria and fungi. The crude hexane extract demonstrated a potent antimicrobial effect against bacteria and a mild effect against fungi. Likewise, the hexane extract of cell cultures of A. hispidissima also showed mild bioefficacy against the select microorganisms.